4) Directions? Which way are my characters traveling to get where they're going?
Again, this is where it's helpful to draw a map, especially if you didn't start one for question 3. You don't want your characters traveling South to reach the villain, when his fortress is to the North. You just need a basic map showing where things are in relation to one another. Don't worry about fancy symbols and map legends until your world is complete. Right now all you need to worry about is where things are and where your characters need to go.